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5 GLP-1RAs in obesity treatment 5.1 Weight loss efficacy GLP-1 receptor agonists exhibit significant weight loss via many molecular routes
Triple hormone receptor agonist retatrutide for metabolic dysfunction-associated steatotic liver disease: a randomized phase 2a trial
Smaller portions, maximum nutrition the perfect support for GLP-1 therapy
Eight major RCTs of GLP-1RAs have investigated the cardiovascular outcomes, including the ELIXA trial of lixisenatide (250), the EXSCEL trial of exenatide ER (251), the LEARDER trial of liraglutide (252), the SUSTAIN-6 trial of subcutaneous semaglutide (253), the HARMONY trial of albiglutide (228), the REWIND trial of dulaglutide (254), the PIONEER trial of oral semaglutide (255), and the SELECT trial of subcutaneous semaglutide (199)
DPP4 is the enzyme that breaks down GLP-1, so by inhibiting DPP4, GLP-1 may hang around in the system longer
