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The electron transport chain (ETC) is integral to aerobic respiration in eukaryotic cells, located within the inner mitochondrial membrane (IMM)

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GLP-1 therapies like Ozempic have also been shown to lower the risk of heart and kidney disease, leading to additional FDA approvals for heart and kidney protection

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PLoS ONE 2018, human dorsal-root-ganglion neurons: GLP-1R agonists do not excite nociceptors directly and have no effect on capsaicin/TRPV1 responses but enhance ATP/P2X signaling, so TRPV1 is excluded as the channel