For each subcutaneous injection, 5 10 6 cancer cells mixed 1:1 with Matrigel (BD Biosciences, 356234) were injected into the flanks of NCG mice
Abbreviations BPH: Benign prostatic hyperplasia COS-ART: controlled ovarian stimulation/assisted reproductive technology CRPC: castration-resistant prostatic cancer COX-2: cyclooxygenase-2 EGF: Epidermal growth factor EMT: epithelial-to-mesenchymal transition FSH: follicle-stimulating hormone GH-RH: growth hormone-releasing hormone GRP: gastrin-releasing peptide GLY: glycine Gn-RH: Gonadotropin Releasing Hormone IGF-I: insulin-like growth factor-1 IVF-ET: in vitro fertilization and embryo transfer LEU: Leucine LH-RH: luteinizing hormone-releasing hormone MEF: mouse embryonic fibroblasts pGHRH-R: pituitary-GH-RH receptor PHE: phenylalanine PSA: prostate-specific antigen TRP: tryptophan TURP: transurethral resection of the prostate References Green, J
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Contains no pigment and has no irritation
A randomized controlled trial by Baker et al
GHK-Cu activates fibroblasts, the cells responsible for collagen and elastin synthesis, and triggers extracellular matrix remodeling through metalloproteinase regulation
