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doi: 10.1016/s0304-3835(01)00797-2 72 XinHDengYCaoJ

Comparison with Protein Biologics Relative to larger protein drugs, peptides often offer advantages in manufacturing, stability, and delivery

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Am J Gastroenterol 95:532535

However, starting at a full dose too often causes side effects like bloating, nausea, or constipation