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Offering locally-adapted animals choices on pastures and rangelands also allows each individual to meet its needs for nutrients and to regulate its intake of secondary compounds by mixing foods in ways that work for that individual (Provenza et al., 2003)

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This observation aligns also with a generally lower correlation in gene expression in hypothalamic neurons of both mice treated with the GIPR antagonist or acyl-GLP-1, and further in mice treated with acyl-GIP or MAR709 (Extended Data Fig