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doi:10.1034/j.1601-183x.2003.00037.x 107. Russo, A

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The disorders clinical manifestations of these disorders are typically nonspecific and may present with multisystemic symptoms [2], including psychomotor retardation, hypotonia, microcephaly, and metabolic acidosis

Furthermore, drug-loaded NRF significantly reduced lacrimal gland inflammation compared to the marketed formulation, which might be attributed to increased CsA solubility and pre-corneal drug retention at the ocular surface