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Vitamin B12 is generally well-tolerated and safe when taken at recommended doses

Vitamin B12 is mainly obtained from animal-derived foods such as meat, eggs, and dairy

High-dose oral B12 (1,000 to 2,000 mcg daily) can actually correct deficiency even in some people with poor absorption, because a small percentage of B12 is absorbed passively (without intrinsic factor)

Take a B12 supplement for targeted health needs, such as a known deficiency, a vegan/vegetarian diet, neuropathy or other nervous system issues, or the formation of red blood cells

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NAD+ metabolism and the control of energy homeostasis: A balancing act between mitochondria and the nucleus