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These components demonstrated strong binding affinity, interacting with five key targets: AKT1, MAPK1, MYC, EGF, and HSP90AA1 [242]
Due to the limit of available articles at the time of search, the initial search was quite broad with a very narrow final evidence base which mainly resulted in case reports or case series, narrative scoping reviews, or small retrospective cohorts
Developmental and early life origins of cardiometabolic risk factors: novel findings and implications
However, there are examples of drugs being withdrawn from the market as more long-term data comes to light
Aug 9 2025;26(16)doi:10.3390/ijms26167703 Castillo LF, Pelletier CM, Heyden KE, Field MS
In recent years, SA has also been identified as a manifestation of the metabolic syndrome associated with insulin resistance independently of obesity [11]
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