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Some studies suggest a high dosage of glutathione is unsafe and may cause severe side effects

Cell Metab 8: 532-539, 2008

Summary, a simple challenge remains: the existing treatments at present offer only symptomatic treatment but not reversal of disease

Although other delivery methods are possible, such as oral delivery (for example, ALA, which is more convenient for patients but is associated with concerns over inter-patient variability in bioavailability and pharmacokinetics, photosensitizing agents are typically administered in clinical settings through intravenous or topical application

FLS are not uniform throughout the body