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This is where urine remains in the bladder longer than it should, which can lead to bladder stones and other complications

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Genetics, appetite regulation, metabolism, fat storage, energy expenditure, GLP-1, GIP, leptin, ghrelin, and insulin may influence weight regulation

We employed a strategy consisting of: (i) using DockTScore within the DockThor docking engine 38 to generate reliable reversible complexes between acrylamide-containing GDP-based inhibitors 7a - i and KRAS G13C , and (ii) refining of these complexes using microsecond MD simulations to explore the proximity of the warhead to Cys13 under native conditions