Your calculated dose is accurate based on what went into the vial, but the actual active compound is lower because some percentage was destroyed by shaking
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Typically resolves with continued use
doi: 10.7326/0003-4819-121-12-199412150-00009 7 IOM (2015)
The single human dataset for musculoskeletal use is a retrospective chart review of sixteen knee-pain patients who paid for intra-articular injections, with subjective improvement reported in fourteen and no control, no blinded assessment, and no objective imaging endpoint
It also lowers triglycerides and cholesterol levels, which can enhance heart health