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In rats, PACAP stimulates GH release from pituitary cell lines and also when infused in vivo (432-434)

This legal requirement applies to all GLP-1 drugs, whether branded (Ozempic, Wegovy, Mounjaro) or compounded formulations

In vivo pharmacological manipulation of TRPA1 was not feasible due to the lack of information on the safety and pharmacokinetic profiles of selective agonists and antagonists 89