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This is a recurring hazard in neurodegeneration drug development, where surrogate measures are seductive precisely because clinical endpoints are slow, noisy, and expensive to move

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324,325 After the OVA challenge, IL-13 expression in BALF of Trx-Tg mice was significantly lower than that in WT mice, while serum levels of IL-13 were comparable

Why consistency matters more than intensity Given the months-long timescale of hair cycling, consistent daily application matters far more than occasional intensive treatments

2B), the cells exhibited a much younger phenotype compared with vehicle control (Fig

Contents hide The FDA Reclassification: What Changed and What It Means To understand the significance of the February 2026 announcement, it helps to understand the regulatory history