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In vitro, we found that in PSCs, high ROS accumulation attributed to high glucose was associated with PSC activation, which was characterized by increased expression of -SMA, accelerated migration, and increased synthesis of ECM proteins such as collagen I, all of which were rescued by GSH treatment

Front Endocrinol (Lausanne) (2019) 10:933

however, many people still don't fully understand precisely why inflammation lies at the root of most health concerns plaguing Americans today

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Melanin Regulation: Skin color-producing Melanin is known to produce skin-darkening skin pigmentation