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All of these timelines are from animal research and may not directly apply to humans (Sikiric et al., 1993)

It is thought that many chronic illnesses, including ME/CFS, originate with reactivation of latent or dormant viruses that are present in the body, caused by a change in physiological conditions (127)

Think of it like trying any new active ingredient

In high fat diet (HFD) and streptozotocin (STZ)-induced type 2 diabetic mice model and HK-2 cells, after treatment with metformin (200 mg/kg/d) for 24 weeks, some indicators of mitophagy (LC3II, Pink1, Parkin, Atg5) were examined

These effects are normal and not usually a cause for concern

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