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The association between N, N, N-trimethyllysine, L-carnitine, and betaine with proteins

The MC4R gene variant (rs17782313) is another example: this gene controls melanocortin signaling, a core pathway for hunger and energy balance

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The underlying mechanisms are multifactorial and not fully understood, but increasing evidence highlights the gutbrain axis and the intestinal microbiome as critical contributors to disease onset and progression (He et al., 2023