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Kidney disease, especially with dialysis

all helping to lower inflammation levels over time

Carnitine is usually formed in the brain, liver, and kidneys

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Oxidative stress affects all aspects, such as inflammation, ED, neuroinflammation, disruption of neurotransmitter secretion, and coagulopathy development, which are responsible for the induction of persistent LC symptoms

J Neurochem 134:36 Gibson GE, Xu H, Chen HL, Chen W, Denton TT, Zhang S (2015) Alpha-ketoglutarate dehydrogenase complex-dependent succinylation of proteins in neurons and neuronal cell lines