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9.93 5.09, P = 0.017), there was no significant difference in the ACT and Mini-AQLQ results

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Large amounts of hepatocyte necrosis during liver failure can lead to the release of HMGB1 from hepatocytes, as HMGB1 has a similar effect to endotoxin, HMGB1 is also involved in the pathogenesis of ALF (46)

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