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More to know Key ingredients: 0.3% pure retinol, soybean oil, peptides Fragrance-free: yes Best Serum for Puffiness: IOPE Expert PDRN Caffeine Shot Serum Why it's worth it: You might associate mature skin with being thinner, drier, and less firmbut as circulation slows and lymphatic drainage becomes less efficient, puffiness can also start to sneak in (and stick around a little longer than it used to)

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An aliquot of the sample was taken for measuring the total protein concentration using a BCA assay kit (Merck Millipore)

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Newman AB, Sanders JL, Kizer JR, Boudreau RM, Odden MC, Hazzouri ZA, A and Arnold AM, (2016) Trajectories of function and biomarkers with age: the CHS All Stars Study