A prespecified secondary analysis of SELECT participants without diabetes showed that semaglutide reduced the composite kidney endpoint by 22% (86), with 75% of participants on RAAS blocker therapy at baseline
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McCoy, MD, MS, associate professor of medicine in the University of Maryland School of Medicine and director of the center for population health in the University of Maryland Institute for Health Computing, said the increased risk early during therapy is likely due to health care professionals being more vigilant with thyroid cancer screening when a person starts GLP-1 therapy
They may be effective when combined with a healthy diet and exercise, but they are not miracle cures
it is taken orally, instead of injected