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These markers are commonly used in experimental bone and connective tissue studies to evaluate vascular activation and endothelial participation in tissue regeneration

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It absorbs nutrients better and sends fewer inflammatory signals throughout the body

In particular, the potential confounding effects of protein-restricted dietary treatment and medical formula intake on the observed metabolomic profiles should be carefully addressed in future studies, in which enrolling newly diagnosed individuals before starting the formula, followed by a series of samples, should help mitigate this limitation

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