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One of the side effects of this drug is it delays gastric emptying, she said

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If similar mechanisms operate in retinal vessels, dual agonism might be associated with reduced transient hypoperfusion, believed to trigger early worsening

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Given that intravesical lidocaine instillation appears to offer relief to a subset of patients but that the relief is short-term (i.e., less than two weeks) and the procedure can be associated with pain, this treatment alternative was designated an Option