The high throughput screening campaign of the substance library provided several hit compounds one of those the drug-like aryl sulfonamide 40 that was subsequently optimized into 41 that is a metabolically stable and reversible IRAP inhibitor
This is its greatest strength as a research tool
Hall BM, Balan V, Gleiberman AS, Strom E, Krasnov P, Virtuoso LP, Rydkina E, Vujcic S, Balan K, Gitlin I, Leonova K, Polinsky A, Chernova OB, Gudkov AV
A faint blue-green tint at the injection site is sometimes reported and is associated with the copper in GHK-Cu (cosmetic only)
Visual Characteristics of Lyophilized GHK-Cu Depending on manufacturing conditions and freeze-drying parameters, lyophilized GHK-Cu may appear as: Fine blue to blue-green powder White to off-white lyophilized cake (depending on copper content) Compact peptide puck adhered to the vial surface Minor variations between vials are normal and generally reflect differences in freeze-drying parameters, formulation composition, or vial geometry during manufacturing
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