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Key Benefits Observed in Clinical Trials Treatment of Erythropoietic Protoporphyria (EPP): MT-1 (Afamelanotide) is FDA-approved for use in patients with EPP, a rare genetic disorder that causes extreme photosensitivity, leading to severe pain and skin damage upon light exposure
Which as a result impairs the absorption of vitamin B12 from food
Similar observations were made with lipopolysaccharide-activated monocytes (14)
(Riederer 2022) Other pathways involve CYP2C8 and CYP2B6
A larger sample of such cases is required for further clarification
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