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95% CI: 3.51-6.21, P=0.0011) ( Mendelian randomization (MR) facilitates the study of the causal relationships between exposure factors and outcomes ( 2 Materials and methods 2.1 Study design Figure 1 showed three key assumptions of this MR study: SNPs are strongly associated with appendectomy or appendicitis

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The cells were resuspended in lysis buffer containing 50 mM Tris-HCl pH 8.0, 400 mM NaCl, protease inhibitor cocktail (Roche)

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