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3.5 Ferroptosis-induced disruption of the bloodbrain barrier in Alzheimers disease The bloodbrain barrier (BBB) is a critical structural interface that maintains central nervous system (CNS) homeostasis by restricting the translocation of blood-derived substances, inflammatory mediators, iron ions, and immune cells into the brain parenchyma through its tight junction architecture

University of British Columbia, Vancouver, Canada

82 developed an ortho-hydroxy-protected aryl sulfate (OHPAS) attachment for payloads containing an aromatic-OH based on highly stable diaryl sulfate structures (Fig