In a study using a lymphoblastoid cell line from patients with late-onset alzheimers disease, catalpol activates the Kelch-like ECH-associated protein 1 (Keap1)/Nrf2/antioxidant response element (ARE) signaling pathway, providing antioxidant and anti-apoptotic effects (Xiang et al., 2024)
AST/Bex also upregulated the expression of ABCA1, LRP1, and/or APOA-I, thereby facilitating cholesterol efflux partially through PPAR/RXR activation, and downregulated cholesterol biosynthesis and esterification
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The total duration of anesthesia was approximately 10 min, and injections were conducted at room temperature (22C)
The effects of ketogenic diet on insulin sensitivity and weight loss, which came first: the chicken or the egg
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