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Description

Depending on dose, a fraction of APAP is converted into a highly reactive toxic intermediate, N-acetyl-p-benzoquinone imine (NAPQI) by several P450 cytochromes

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The copper(II) ion is coordinated by the glycine amino terminus, the deprotonated glycine to histidine peptide-bond nitrogen, and the histidine imidazole nitrogen, giving the complex its characteristic colour and stability

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