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Furthermore, proBDNF could serve as a reservoir for the mature molecule, and an increase in proBDNF suggests a larger BDNF deposit that is likely associated with greater genetic transcription (e.g., epigenetic regulation)

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Additional compounds worth researching include AOD-9604 , tesofensine , lipo-C peptide , and the emerging GLP-3 peptide

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Further, those with higher B12 levels and taking high dose vitamins had better outcomes with stroke, death, and heart events compared to those with lower B12 levels and taking low dose vitamins (3)