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Increased need for magnesium with the use of combined oestrogen and calcium for osteoporosis treatment

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A study published in the New England Journal of Medicine showed a mean weight reduction of 24.2% at 48 weeks with the highest dose (12 mg), suggesting a potent step-change in efficacy

Im sure there are gonna be people that are on these medications who are gonna end up relapsing

Common side effects include nausea, vomiting, diarrhea, constipation, abdominal discomfort, fatigue, and headaches especially when first starting or increasing the dose