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GLP-1RAs pose risks of severe eye complications, particularly worsening diabetic retinopathy with rapid and significant HbA1c reduction
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Wald NJ, Watt HC, Law MR, Weir DG, McPartlin J, and Scott JM (1998)
Mayo Clinic says low blood sugar can occur with semaglutide when used with insulin or sulfonylureas, and also when meals are delayed or missed
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Regulatory status: FDA-approved in 1959 as a short-term adjunct for weight reduction in adults with exogenous obesity
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