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As individuals age, the expression of IL-11 increases in cells and tissues, leading to fat accumulation and muscle loss

In the interim, the supply-demand imbalance in high-purity GLP-1 peptide CDMO capacity is giving existing capacity holders unprecedented pricing power and making multi-year capacity reservation agreements with take-or-pay clauses the standard commercial structure for late-stage peptide programmes

95% CI, 0.35-0.86), but SGLT2 inhibitors were not (OR = 1.2

Review article: the gut microbiome in inflammatory bowel disease-avenues for microbial management

doi:10.1073/pnas.89.18.8641

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