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C.YelshanskayaM

Molecular Formula (reported, with DAC): CHNO Molecular Weight (reported): ~3647 g/mol Sequence (with DAC descriptor per position): H-Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-(N^-maleimidopropionyl-)Lys-NH

Thus, exposure to spike protein inhibits recovery of apical CFTR from the endosomal recycling process

The supernatant (nuclear fraction) was isolated by centrifuging at 12,000 rpm for 30 min at 4 C

11.2.0 software (SAS Institute, Cary, NC, USA)

The "no DAC" designation indicates the absence of Drug Affinity Complex, resulting in a relatively short half-life of approximately 30 minutes