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Efficacy and safety of cotadutide, a dual glucagon-like peptide-1 and glucagon receptor agonist, in a randomized phase 2a study of patients with type 2 diabetes and chronic kidney disease
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Patients in the ALC group also had scores on the FACT trial outcome index subscale (FACT-TOI), an overall measure of function, that were on average 3.5 points lower (worse) than those among their placebo counterparts (P = .03)
Begin with 500mg once daily, taken with the largest meal of the day
GLP-1 microdosing uses sub-therapeutic doses of Tirzepatide doses below the standard weight-loss range to deliver the metabolic and appetite-regulating benefits of GLP-1 therapy with a significantly reduced side effect profile
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