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If the presence of an initial stressor is prolonged, the HPA axis will become chronically activated and trigger the overproduction of cortisol which, over time, will result in a reduction in cortisol levels (427)

[DOI] [PubMed] [Google Scholar] 143.Zhang J, Hupfeld CJ, Taylor SS, Olefsky JM, Tsien RY

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The altered expression of key targets revealed a potential association with BRCA, which were consistent with previous studies

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