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A study examining weight outcomes in patients using GLP-1 agonists found that those concurrently taking any antidepressant, including bupropion, lost slightly less weight on average compared to those not taking antidepressants

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Multimodal treatments tailored to different clinical presentations and potential underlying pathogenic mechanisms are recommended by current guidelines

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Similarly, in the NAFLD mouse model, mice fed with a high-fat diet showed reduced hepatic GLP-1R expression, which was reversed by NaB treatment and accompanied by markedly alleviated liver steatosis