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At the pathogenic level, PsO and PsA share core inflammatory mechanisms driven by dysregulation of the IL17/IL23 and Tumour Necrosis Factor (TNF)- cytokine axes (14), contributing to keratinocyte hyperproliferation, synovial inflammation, and enthesial disease (1518)

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Answer: When anxiety is driven by correctable biology, such as a hormone imbalance, a disrupted cortisol rhythm, or nutrient depletion, addressing those drivers can meaningfully reduce or resolve symptoms over time, though timelines vary by individual

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Acetaldehyde is an aldehyde, which is why it is included in both terms

Any such combination study should be designed with appropriate controls and conducted strictly within a laboratory setting by qualified researchers