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When cortisol is chronically elevated, the body prioritizes survival over reproduction, and sexual interest declines accordingly

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GLP-1 receptors are expressed not only in the gut and pancreas but also in brain regions involved in reward, motivation, and stress regulation, including areas linked to the mesolimbic dopamine system the core circuitry of addiction

Neuroreport 31 , 12831288 (2020)

Marks first became aware of the challenge of hypoglycemia while working as a trainee in clinical chemical pathology at the National Hospital for Neurology and Neurosurgery and Institute of Neurology in London

Retatrutide is still investigational and is not currently licensed by the MHRA for weight loss in the UK