Curcumin scavenge ROS, inhibits IKK-S-nitrosylation [517], downregulates NLRP3 [518]/STAT3 [519], and regulates follicular helper T cell (Tfh) subsets [520, 521]
But theres limited research into their effectiveness
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Unfortunately, the adopted reimbursement criteria make it possible to include only about 57% of patients with FH (due to the required high LDL-C concentration despite treatment) and a relatively small group of post-MI patients (mainly due to the need to include them within 12 months of MI onset)