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Cleveland Clinic and Mayo Clinic both note that these medicines should be started carefully and usually need dose escalation under medical supervision

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Davies said several GLP-1/glucagon dual agonists have moved on to phase 2 or phase 3 trials, including survodutide (Boehringer Ingelheim), efinopegdutide (Hanmi Pharmaceutical), mazdutide (Eli Lilly and Innovent) and pemvidutide (Altimmune)

Redness, swelling, or pain at the site can indicate complications