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As an example, platelets from G6PD-deficient individuals exhibit reduced G6PD enzymatic activity (30), affecting the availability of reduced glutathione required for platelet aggregation (89) and of NADPH needed for biosynthesis of fatty acids and phospholipids (90) ( Figure 1A-3 )

[Note: Cyto-chrome P450 (CYP) enzymes are actually a superfamily of related, heme-containing monooxygenases that participate in a broad variety of reactions

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TB-4 Preclinical wound-healing data (cardiac, dermal, neural)