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Many are confined to a re-discussion of Nrf2 and HDAC inhibition, lacking integration with its biosynthetic origins and failing to synthesize the rapidly expanding body of evidence on novel and underappreciated mechanisms
We thought the answer could rely on a family of enzymes called gamma-glutamyl-transferases (GGT)
This is particularly relevant for bisphosphonates (alendronate, risedronate), tetracycline and quinolone antibiotics, levothyroxine, integrase inhibitors (dolutegravir, bictegravir), penicillamine, and mycophenolate
doi: 10.4103/nah.NAH_74_16, 35 CoulyS.CarlesA.DenusM.Benigno-AntonL.MaschatF.MauriceT
Liposomal absorption is nothing unknown even in nature: for example, in breast milk, nutrients are protected by fatty substances (phospholipids) so that the infant's body can absorb and utilize them as best as possible