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These ligands all bind to D2-like dopamine receptors, including D3, suggesting that D2-like receptors may also affect mast cell activity, although this cell type is actually derived from basophils, and it is not clear if it is entirely representative of mast cell biology (Passante and Frankish, 2009)

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February 20, 2020

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Manifestations of hepatic oxidative damage include dysregulation of lipid metabolism (leading to steatosis), hepatocyte degeneration and death, and activated immune response (leading to inflammation and fibrosis/cirrhosis)