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5-Amino-1MQ inhibits the enzyme NNMT (nicotinamide N-methyltransferase), which preserves intracellular NAD+ and activates AMPK-dependent mitochondrial fat oxidation

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Within the mitochondria, the production of H 2 S by MPST contributes to enhanced electron flow and mitochondria bioenergetics, the consequences of which are enhanced cellular longevity