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However, observations similar to GLT1 were noted in only 3 patients, where a low replicator variant evolved into a high replicator variant after LTX

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( e ) Cells expressing empty vector (EV) or CCNE1 were treated with the IDH1 inhibitor or the PARP inhibitors veliparib (left) or niraparib (right) alone or in combination (n = 4 technical replicates representative from 2 independent experiments in each cell line)

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