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However, a larger fraction of the estrogens was excreted as 2- and 4-hydroxylated and -methylated metabolites in the COC users than in the controls, with the largest shift visible for the 2-OH-estrogens (5.1% in controls vs

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Although HDACis are capable of restoring Class I-III G6PD variant activity to that of WT or greater in erythroid precursor cells, histone deacetylation is important for DNA compression, nuclear extrusion, and erythroid maturation [83-85]

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