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Understandably, some people who have a sulfa allergy might think that they are allergic to sulfites, too, because the names of the two chemicals are similar

However, the initial report of this variant affecting -endorphin potency has not been replicated (Beyer et al., 2004

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While the products contain well-researched nutrients that are taken by millions of people around the world, it is possible they could interfere with certain medications

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Systemic rather than localized gut focus: While injectables can still benefit GI health indirectly, they are not as targeted to the mucosal lining as oral forms