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In this study, three assumptions of MR were tested to ensure the reliability of the study results

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[12] Very high cumulative exposure over months may encourage calcium deposition in soft tissues such as the renal parenchyma or coronary arteries, an outcome implicated in observational studies linking supra-physiological 25-hydroxyvitamin D levels with vascular calcification and heightened fracture risk in frail elders

[Google Scholar] 83.Xu C., Sun L., Ren F., Huang P., Tian Z., Cui J., Zhang W., Wang S., Zhang K., He L., et al