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In a report by Olivia Clinic , serious side effects such as kidney failure or blood poisoning can occur when the dosage is much higher than what is required

The RER and energy expenditure (via the Weir equation) were calculated, while ambulatory activity was determined simultaneously

In addition, mRNA expression of key genes in lysosomes, including acid hydrolases (such as cathepsin A/D), LAMP-1 and LAMP-2, was significantly upregulated following sepsis, hinting that overloaded lysosomal function might be an early marker for poor outcomes for patients with sepsis 22

Toxicol Pathol 33, 68