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In this regard, it has been shown that SSTR5 exerts antiproliferative and antisecretory effects in somatotroph by coupling with the inhibitory G protein G oA , independently of cAMP reduction, suggesting a dissociation between these pathways (11, 42)

If fatigue emerges despite adequate nutrition and biomarker supplementation, dose reduction or temporary pause may be warranted

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Radiotherapy resistance (RR) can occur due to multiple factors, including genetic mutations, altered DNA repair mechanisms, and changes in the tumor microenvironment (59)

A slight calorie deficit (200500 calories below maintenance)

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